Researchers blast as 'immoral'
failure to test anti-virus combo
French researchers are urging a major expansion of testing of Covid-19 patients with chloroquine and Azithromycin, saying that not to do so is "immoral."
Citing the Hippocratic Oath, researchers at the Institut Hospitalier Universitaire Méditerranée Infection, based in Marseilles, said their group would go ahead and treat anyone with Covid-19 with the combination as long as the patient was not barred because of potential drug reactions. The group said it had decided:
The statement was signed by Doctors Philippe Brouqui, Jean-Christophe Lagier, Matthieu Million, Philippe Parola, Didier Raoult, and Marie Hocquart.
The institute, known as the Mediterranean Infection Foundation in English, aims to condense the means of fighting infectious diseases, the leading cause of death in the world (17 million deaths per year) and in particular the three world killers HIV, tuberculosis and malaria.
The research team reported recently that it had achieved astonishing results with the chloroquine-Azithromycin treatment, knocking out Covid-19 within six days in 75 percent of patients.
Researchers report knockout punch of Covid-19
https://invisiblepaul.blogspot.com/2020/03/french-researchers-preliminary-results.html
The French team's decision is reminiscent of the decision of AIDS researchers, some 20 years ago, to suspend controlled studies of the "AIDS cocktail" because it was proving so effective that it was unethical to deprive the control group of the medicines.
A similar issue erupted in the 1950s when the March of Dimes advocated the use of Bayesian statistical methods in order to get the Salk vaccine into usage without being pedantic and risking more childhood cases. By contrast, some officials insisted on using unvaccinated children in control groups in order to obtain standard statistical results, and, in fact, that course of action was taken. Hence, the vaccine's statistical success meant that a number of children were left to contract polio.
Citing the Hippocratic Oath, researchers at the Institut Hospitalier Universitaire Méditerranée Infection, based in Marseilles, said their group would go ahead and treat anyone with Covid-19 with the combination as long as the patient was not barred because of potential drug reactions. The group said it had decided:
# For all febrile [symptomatic] patients who come to consult us, to practice the tests for the diagnosis of infection with Covid 19."We think that it is not moral that this association is not systematically included in the therapeutic trials concerning the treatment of Covid-19 infection in France," the researchers said in a public statement.
# For all infected patients -- many of whom are not very symptomatic and have pulmonary lesions on CT as soon as the diagnosis is made -- begin treatment with hydroxychloroquine (200 milligrams three times per day for 10 days) plus Azithromycin (500 mg on the 1st day followed by 250 mg per day for 5 more days), within the framework of the precautions for use of this combination (with in particular an electrocardiogram on D0 and D2), and outside of marketing authorization.
In cases of severe pneumonia, a broad-spectrum antibiotic is also used.
The statement was signed by Doctors Philippe Brouqui, Jean-Christophe Lagier, Matthieu Million, Philippe Parola, Didier Raoult, and Marie Hocquart.
The institute, known as the Mediterranean Infection Foundation in English, aims to condense the means of fighting infectious diseases, the leading cause of death in the world (17 million deaths per year) and in particular the three world killers HIV, tuberculosis and malaria.
The research team reported recently that it had achieved astonishing results with the chloroquine-Azithromycin treatment, knocking out Covid-19 within six days in 75 percent of patients.
Researchers report knockout punch of Covid-19
https://invisiblepaul.blogspot.com/2020/03/french-researchers-preliminary-results.html
The French team's decision is reminiscent of the decision of AIDS researchers, some 20 years ago, to suspend controlled studies of the "AIDS cocktail" because it was proving so effective that it was unethical to deprive the control group of the medicines.
A similar issue erupted in the 1950s when the March of Dimes advocated the use of Bayesian statistical methods in order to get the Salk vaccine into usage without being pedantic and risking more childhood cases. By contrast, some officials insisted on using unvaccinated children in control groups in order to obtain standard statistical results, and, in fact, that course of action was taken. Hence, the vaccine's statistical success meant that a number of children were left to contract polio.
No comments:
Post a Comment